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Giuseppe and Pietro Simi emigrated from Tuscany in the 1840s, looking to make their fortune panning for gold in California – but soon switched to making wine. From their base in Healdsburg, the brothers made their first vintage under the Montepulciano Cellars name in 1876. Business took off, but an outbreak of flu sadly saw the brothers die suddenly, just a few weeks apart. Giuseppe’s daughter Isabelle took over in 1904, then just 18 years old.